The first official Scream 4 photo with Courteney Cox Arquette and GhostFace has been released. Scream 4 is directed by Wes Craven and stars David Arquette, Neve Campbell, Courteney Cox Arquette, Emma Roberts, Hayden Panettiere, Rory Culkin, Nico Tortorella, and Erik Knudsen. In the Scream 4 photo, Courteney Cox seems to be seems to be investigating a strange noise. Uh oh, that is a no no. Doesn’t she remember the rules from Scream 1? Check out the photo below. Scream 4 opens on April 15, 2011.